الأربعاء، 2 نوفمبر 2011

causes of cancer

causes of cancer

Cancer is ultimately the result of cells that uncontrolled grow . Normal cells in the body follow  regular path of growth, division, and death. Programmed cell death is called (apoptosis), and when this process breaks down, cancer begins to form. Unlike regular cells, cancer cells  no apoptosis and instead continue to grow and divide. This leads to a mass of abnormal cells that grows out of control

Genes - the DNA type

  normal cell division process: oncogenes tell cells when to divide, tumor suppressor genes tell cells when not to divide, suicide genes control apoptosis and tell the cell to kill itself if something goes wrong, and DNA-repair genes instruct a cell to repair damaged DNA.
Cancer occurs when a cell's gene mutations make the cell unable to correct DNA damage and unable to commit suicide.leading to uncontrollable cell growth.

Carcinogens

Carcinogens are a class of substances that are directly responsible for damaging DNA,  
Tobacco, asbestos, arsenic, radiation such as gamma and x-rays 
the sun, and compounds in car exhaust fumes are all examples of carcinogens. When our bodies are exposed to carcinogens, free radicals are formed that try to steal electrons from other molecules in the body. Theses free radicals damage cells and affect their ability to function normally.

familial causes

Cancer can be the result of a genetic predisposition that is inherited from family members. It is possible to be born with certain genetic mutations or a fault in a gene that makes one statistically more likely to develop cancer later in life.

Other medical factors


As we age, there is an increase in the number of possible cancer-causing mutations in our DNA. This makes age an important risk factor for cancer. Several viruses have also been  viruses cause cancer
human papillomavirus cause of cervical cancer

hepatitis B and C causes of liver cancer
  Epstein-Barr virusa cause of some childhood cancers

 

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